Rulers:
• Carlos I, King of Spain (1516-1556)
• Charles V, Holy Roman Emperor (1519-1558)
• Federico II Gonzaga, 5th Marquis of Mantua (1519-1530)
• François I, King of France (1515-1547)
• Henry VIII, King of England (1509-1547)
• Henry VIII, Lord of Ireland (1509-1542)
• Leo X (Giovanni di Lorenzo de’ Medici), Pope (1513-1521)
• Leonardo Loredan, Doge della Repubblica di Venezia (1501-1521)
Deaths:
• Giovanni di Lorenzo de’ Medici (1475-1521), Pope Leo X (1513-1521)
• Loredan, Leonardo (1436-1521)
Art:
• Dürer, Albrecht (1471-1528): Portrait of a Man (1521)
• Dürer, Albrecht (1471-1528): The Lamentation of Christ (1521)
• Tiziano (c.1488-1576): Bacco e Arianna (1520-23)