| Born | April 18 | 1480 | Subiaco (Italia) |
| Died | June 24 | 1519 | Ferrara (Italia) |
| Father | Rodrigo Borgia (1431-1503), Pope Alexander VI (1492-1503) |
| Brother | Cesare Borgia (1475-1507) |
| Husband (m.1502–1519) | Alfonso I d’Este, Duke of Ferrara (1476-1534) |
| Sister-in-law | Isabella d’Este, Marchesa di Mantova (1474-1539) |
| Nephew-in-law | Federico II Gonzaga, 1st Duke of Mantua (1500-1540) |
| Sister-in-law | Beatrice d’Este, Duchess of Milan (1475-1497) |
| Brother-in-law | Ludovico Sforza (1452-1508) |